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Packers vs. Browns Odds & Betting Predictions - September 21, 2025

Packers at Browns

5:00 pm • FOX
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Green Bay Packers

0-1
@

Cleveland Browns

3-14

Packers at Browns Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Packers
0-1
N/A
N/A
N/A
Browns
3-14
N/A
N/A
N/A
location pinSunday 5:00 p.m.
September 21, 2025
Huntington Bank FieldCleveland

Packers vs. Browns Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Packers vs. Browns Public Betting Percentages

Away Logo

Packers

Public

Home Logo

Browns

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Browns are 2-3 in their last 5 games.
  • Browns are 2-3 in their last 5 games against the spread
  • Browns are 2-7 in their road games against the spread
  • The totals have gone OVER in 3 of Browns' last 5 games
  • The totals have gone OVER in 3 of Browns' 8 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Browns		4-132-62-70-44-9
Packers		8-8-15-43-3-16-62-2-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Browns		7-103-54-52-25-8
Packers		8-8-13-5-14-35-6-13-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Browns		3-14N/AN/A0-43-10
Packers		11-6N/AN/A9-32-3

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jan 4th@BALL 10-35+19.5 LO 42BAL +1300
Dec 29thMIAL 3-20+3 LU 32.5MIA +150
Dec 22nd@CINL 6-24+10 LU 46CIN +400
Dec 15thKCL 7-21+4.5 LU 41.5KC +187
Dec 8th@PITL 14-27+6 LU 42.5PIT +215

Browns vs. Packers Injury Updates

Browns Injuries

  • Joel Bitonio
    G

    Bitonio is questionable with back

    Questionable

  • Jordan Hicks
    LB

    Hicks is out with concussion

    Out

  • David Njoku
    TE

    Njoku is out with knee

    Out

  • Ogbo Okoronkwo
    DE

    Okoronkwo is questionable with knee

    Questionable

  • Denzel Ward
    CB

    Ward is out with shoulder

    Out

  • Joe Tryon-Shoyinka
    DE

    Tryon-Shoyinka is questionable with ankle

    Questionable

  • Teven Jenkins
    G

    Jenkins is out with calf

    Out

  • Jeremiah Owusu-Koramoah
    LB

    Owusu-Koramoah is out with neck

    Out

  • Pierre Strong
    RB

    Strong is out with concussion

    Out

  • Jerome Ford
    RB

    Ford is out with ankle

    Out

  • Michael Woods
    WR

    Woods is questionable with knee

    Questionable

  • Cedric Tillman
    WR

    Tillman is out with concussion

    Out

  • Cameron Mitchell
    CB

    Mitchell is questionable with knee

    Questionable

  • Blake Whiteheart
    TE

    Whiteheart is questionable with knee

    Questionable

  • Mike Hall
    DT

    Hall is questionable with knee

    Questionable

  • Myles Harden
    DB

    Harden is questionable with tibia

    Questionable

Packers Injuries

  • Jaire Alexander
    CB

    Alexander is out with knee

    Out

  • Mecole Hardman
    WR

    Hardman is out with knee

    Out

  • Aaron Banks
    G

    Banks is out with knee

    Out

  • Nate Hobbs
    CB

    Hobbs is questionable with illness

    Questionable

  • Zayne Anderson
    S

    Anderson is out with concussion

    Out

  • Quay Walker
    LB

    Walker is questionable with ankle

    Questionable

  • Christian Watson
    WR

    Watson is out with knee

    Out

  • Brenton Cox
    DE

    Cox is questionable with foot

    Questionable

  • Jordan Morgan
    OL

    Morgan is out with shoulder

    Out

  • MarShawn Lloyd
    RB

    Lloyd is out with hamstring

    Out

  • Ty'Ron Hopper
    LB

    Hopper is questionable with ankle

    Questionable

  • Evan Williams
    DB

    Williams is questionable with quad

    Questionable

See more NFL Injuries Right Arrow
Depth Charts
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Starter2ND3RD4TH
QBDeshaun WatsonJameis WinstonDorian Thompson-Robinson
RBJerome FordPierre StrongD'Onta Foreman
WRJerry JeudyCedric TillmanJames Proche
TEDavid NjokuJordan Akins
LTJames HudsonHakeem AdenijiLorenzo Thompson
LGJoel BitonioMichael DunnJavion Cohen
CEthan PocicNick Harris
RGWyatt TellerZak Zinter
RTDawand JonesGermain IfediRoy Mbaeteka
LDEMyles GarrettOgbo OkoronkwoIsaiah McGuire
LDTMaurice HurstJowon Briggs
RDTShelby HarrisMike HallSam Kamara
RDEAlex Wright
WLBJeremiah Owusu-Koramoah
MLBJordan HicksMohamoud Diabate
SLBDevin BushNathaniel WatsonWinston Reid
LCBDenzel Ward
SSGrant DelpitRodney McLeod
FSJuan ThornhillRonnie HickmanChristopher Edmonds
RCBMartin EmersonTony Brown
PCorey Bojorquez
HCorey Bojorquez
PRJames Proche
KRPierre StrongJerome Ford
LSCharley Hughlett
RWRElijah MooreDavid BellJamari Thrash
NBCameron MitchellMyles Harden
KDustin Hopkins
LWRMichael Woods

Packers vs. Browns Odds Comparison

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Packers at Browns Team Totals

MatchupOverUnder
Packers
0-1
N/A
N/A
Browns
3-14
N/A
N/A