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Packers vs. Browns Odds & Betting Predictions - September 21, 2025

Packers at Browns

5:00 pm • FOX
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Green Bay Packers

2-0
@

Cleveland Browns

0-1

Packers at Browns Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Packers
2-0
-6.5
-7.5-110
o42.5-110
-350
Browns
0-1
u43.5
+7.5-110
u42.5-110
+280
location pinSunday 5:00 p.m.
September 21, 2025
Huntington Bank FieldCleveland
thermometer image67°Fahrenheit
rain image37%Rain
wind image10Wind

Packers vs. Browns Props

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Line Movement Tracker

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Packers vs. Browns Public Betting Percentages

Away Logo

Packers

Public

Home Logo

Browns

22%

Bets%

78%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Browns are 0-1 in their last 5 games.
  • Browns are 1-0 in their last 5 games against the spread
  • The totals have gone OVER in 0 of Browns' last 1 games
  • The totals have gone OVER in 0 of Browns' 1 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Browns		1-01-0N/AN/A1-0
Packers		2-02-0N/A2-0N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Browns		0-10-1N/AN/A0-1
Packers		0-20-2N/A0-2N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Browns		0-1N/AN/AN/A0-1
Packers		2-0N/AN/A2-0N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 7thCINL 16-17+4.5 WU 47.5CIN +185
Aug 23rdLAW 19-17-10 LU 37CLE -550
Aug 16th@PHIW 22-13+2.5 WU 36.5CLE +120
Aug 8th@CARW 30-10+5.5 WO 33.5CLE +210
Jan 4th@BALL 10-35+19.5 LO 42BAL +1300

Browns vs. Packers Injury Updates

Browns Injuries

  • Mike Hall
    DT

    Hall is out with knee

    Out

Packers Injuries

  • Micah Parsons
    DE

    Parsons is questionable with back

    Questionable

  • Nate Hobbs
    CB

    Hobbs is questionable with knee

    Questionable

  • Zayne Anderson
    S

    Anderson is questionable with knee

    Questionable

  • Christian Watson
    WR

    Watson is out with knee

    Out

  • MarShawn Lloyd
    RB

    Lloyd is out with hamstring

    Out

  • Barryn Sorrell
    DE

    Sorrell is questionable with knee

    Questionable

See more NFL Injuries Right Arrow
Player Stats
  • passing yards
    Joe Flacco logo
    Joe Flacco
    290
    pyds
  • passing touchdowns
    Joe Flacco logo
    Joe Flacco
    1
    ptd
  • rushing yards
    Dylan Sampson logo
    Dylan Sampson
    29
    ryds
  • rushing touchdowns
    Raheim Sanders logo
    Raheim Sanders
    1
    rtd
Depth Charts
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Starter2ND3RD4TH
QBJoe FlaccoDillon GabrielShedeur SandersDeshaun Watson
RBJerome FordQuinshon JudkinsDylan SampsonAhmani Marshall
WRJamari ThrashDeAndre CarterGage LarvadainCade McDonald
TEDavid NjokuHarold FanninBlake WhiteheartBrenden BatesSal Cannella
LTDawand JonesCornelius Lucas
LGJoel BitonioTeven Jenkins
CEthan PocicLuke Wypler
RGWyatt TellerZak Zinter
RTJack Conklin
LDEAlex WrightIsaiah McGuireJulian OkwaraK.J. Henry
RDEMyles GarrettJoe Tryon-ShoyinkaCameron Thomas
WLBDevin BushJerome BakerWinston Reid
MLBCarson SchwesingerMohamoud DiabateEaston Mascarenas-Arnold
LCBDenzel WardDom Jones
SSGrant DelpitRayshawn JenkinsDonovan McMillon
FSRonnie HickmanDamontae KazeeChristopher Edmonds
RCBGreg Newsome
PCorey Bojorquez
HCorey Bojorquez
PRDeAndre CarterGage LarvadainKaden Davis
KRDeAndre CarterKaden Davis
LSRex Sunahara
DTMason GrahamMike HallSam KamaraRalph Holley
NTMaliek CollinsShelby HarrisAdin Huntington
LWRCedric TillmanDavid Bell
RWRJerry JeudyIsaiah BondKaden Davis
NBCameron MitchellMyles HardenLaMareon James
KAndre Szmyt
Team Stats

Passing

457
YDS
278
35/53
Comps/Atts
31/45
9.057
YPA
6.444
4/0
TDs/INTs
1/2
2/23
Sacks/Yards
2/12

Rushing

213
Rush Yards
49
55
Attempts
24
3.873
YPC
2.042
2
TDs
1

Turnovers

Fumbles Lost
0
Interceptions
2

Efficiency

6/9 66.67%
Redzone
2/3 66.67%
9/22 0%
3rd Down
9/16 0%
1/2 0%
4th Down
2/3 0%

First Downs

36
Total
22
22
Pass
13
10
Rush
5
4
Penalty
4

Misc

/
Penalties/Yards
/
Possession

Packers vs. Browns Odds Comparison

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Packers at Browns Team Totals

MatchupOverUnder
Packers
2-0
N/A
N/A
Browns
0-1
N/A
N/A