49ers vs. Falcons Odds & Betting Predictions - October 25, 2026

49ers at Falcons

5:00 pm • FOX
14 - 3

49ers at Falcons Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
49ers
6-0
-4.5
-2.5-113
o49.5-115
-145
Falcons
2-4
u47.5
+2.5-106
u49.5-107
+121
location pinSunday 5:00 p.m.
October 25, 2026
Mercedes-Benz StadiumAtlanta
49ers vs. Falcons Expert Picks
YBK Picks.com
Last 30d: 43-44-2 (-7.9u)
ATL +2.5-105
3u
Stuck 🚨
Stuck 🚨
Last 30d: 68-74-2 (+3.0u)
ATL +3.5-105
0.5u
Don’t think 49ers can lay over a Fg here in brutal spot hwith no WRs even if Falcons might be out of LBs
Mike McNamara
Mike McNamara
Last 30d: 82-69-2 (+4.6u)
ATL +3.5-105
0.35u
Sean Koerner🔮
Sean Koerner🔮
Last 30d: 46-62-0 (-0.2u)
Z.Branch o1.5 Recs+144
0.35u
Going out on a “limb” here with Branch, who I’ve been referring to as Temu Zay Flowers. He’s still mostly a gadget/return guy with a limited offensive role as a rookie, which was expected. But we’ve seen his playing time trend up, and when he is on the field they’re using him in motion a ton and actually designing looks for him. That’s why the 26% 1st read rate stands out. His targets tend to be high percentage stuff underneath, so I actually prefer Over 1.5 receptions at plus money to his 7.5 rec yard line. Olamide Zaccheaus is also banged up and questionable. If he’s out, this obviously gets even better, but even if he’s just limited I’d expect that to mean a few more snaps for Branch. I have 2+ catches closer to a coin flip
C.McCaffrey u15.5 Rush Att-128
0.64u
The 6-0 49ers are “only” 2.5-point favorites here, so there’s at least a chance they end up in a rarer trailing game script than we’ve seen so far. Either way, I’m expecting San Francisco’s overall rushing volume to come down a bit, and with the WR room so banged up now that Mike Evans is out, I could see more snaps with CMC and Black on the field together, with McCaffrey flexed out into the slot/at WR and Black handling the backfield work. Using CMC more as a pass catcher and extension of the run game makes a lot of sense here instead of just banging him 16+ times on the ground. Black can take some of that early down work, keep CMC a little fresher and still let them manufacture touches for him through the air. The 49ers also use Purdy on QB sneaks in short yardage spots, which takes away another path to extra carries. I have CMC closer to 14.5 rushing attempts, with around a 61% chance to stay under 15.5.
Doug Ziefel
Doug Ziefel
Last 30d: 395-395-9 (+31.5u)
M.Penix u0.5 Int-120
0.6u
Z.Branch o9.5 Rec Yds-107
0.54u
C.McCaffrey o5.5 Recs-110
0.55u
J.Watkins o1.5 Recs-130
0.65u
Z.Branch o1.5 Recs+100
0.5u
SF -3.5-105
0.53u
Ryan Minion
Ryan Minion
Last 30d: 239-222-3 (+34.0u)
B.Robinson o29.5 Rec Yds-113
1.13u
D.London Anytime TD Scorer Yes+125
1u
Grant Neiffer
Grant Neiffer
Last 30d: 22-75-4 (+0.8u)
B.Robinson 50+ Receiving Yards Yes+430
0.05u
B.Robinson o26.5 Rec Yds-114
0.57u
B.Robinson 70+ Receiving Yards Yes+1200
0.05u
B.Robinson 60+ Receiving Yards Yes+669
0.05u
B.Robinson 80+ Receiving Yards Yes+1680
0.05u
B.Robinson 90+ Receiving Yards Yes+2600
0.05u
OldSchool0909
Last 30d: 49-53-1 (+0.6u)
ATL +2.5-104
1u
Collin Whitchurch
Collin Whitchurch
Last 30d: 112-145-3 (+1.5u)
C.McCaffrey u15.5 Rush Att-120
0.6u
Z.Branch o1.5 Recs+160
0.5u
Over 49.5-110
0.55u
Doug Kezirian
Doug Kezirian
Last 30d: 7-8-1 (-2.4u)
ATL +3-110
1.1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 109-111-4 (+19.0u)
ATL +3.5-114
1.14u
B.Robinson o30.5 Rec Yds-115
1.15u
Brandon Anderson
Brandon Anderson
Last 30d: 30-96-0 (-12.2u)
Under 50-110
0.75u
Brandon’s playground pod Week 6
C.McCaffrey 6+ Receptions Yes+145
0.85u
Brandon’s playground pod Week 6
C.McCaffrey 7+ Receptions Yes+245
0.5u
Brandon’s playground pod Week 6
C.McCaffrey 9+ Receptions Yes+800
0.15u
Brandon’s playground pod Week 6
G.Kittle Anytime TD Scorer Yes+130
1u
Brandon’s playground pod Week 6
Kyle Murray
Kyle Murray
Last 30d: 146-138-9 (+10.7u)
Z.Branch o9.5 Rec Yds+100
1u
Z.Branch 20+ Receiving Yards Yes+223
0.75u
Z.Branch 30+ Receiving Yards Yes+410
0.5u
Z.Branch 40+ Receiving Yards Yes+800
0.25u
Z.Branch 50+ Receiving Yards Yes+1600
0.15u
K.Herbert o7.5 Rush Yds-107
1.07u
Austin Pendergrass
Austin Pendergrass
Last 30d: 72-47-0 (+12.1u)
SF -146
0.5u
Frank Ammirante
Frank Ammirante
Last 30d: 97-92-0 (-8.7u)
ATL +3.5-105
1.05u
B.Robinson o18.5 Rush Att-109
1.09u
Gilles Gallant
Gilles Gallant
Last 30d: 22-63-1 (-4.8u)
J.Watkins Anytime TD Scorer Yes+600
0.25u
Nick Giffen
Nick Giffen
Last 30d: 45-119-0 (+2.5u)
Over 50-107
0.57u
K.Pitts First Touchdown Scorer Yes+1900
0.15u
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 40-99-0 (-8.3u)
C.McCaffrey 6+ Receptions Yes+145
0.69u
C.McCaffrey 7+ Receptions Yes+245
0.41u
C.McCaffrey 9+ Receptions Yes+800
0.13u
G.Kittle Anytime TD Scorer Yes+130
0.77u
Adam Kaufman
Adam Kaufman
Last 30d: 337-311-12 (-9.9u)
SF -155 (1H)
0.5u
SF -158 (2Q)
0.5u
SF -144 (1Q)
0.5u
Over 9.5 (1Q)-122
0.5u
💰🦡 Jake
💰🦡 Jake
Last 30d: 96-107-1 (+19.9u)
ATL +114 (1H)
1u
Alex Hinton
Alex Hinton
Last 30d: 98-105-1 (-3.8u)
C.McCaffrey o5.5 Recs-102
1u
John Feltman
John Feltman
Last 30d: 104-59-1 (+28.6u)
ATL +4.5-105
0.93u
Over 50-110
0.97u
Babs .
Babs .
Last 30d: 47-35-1 (+6.6u)
Z.Branch o8.5 Rec Yds-118
1.33u
Charlie DiSturco
Charlie DiSturco
Last 30d: 111-192-1 (+15.2u)
B.Robinson o29.5 Rec Yds-113
0.56u
C.McCaffrey o5.5 Recs-112
0.56u
Over 49.5-115
0.57u
Derek Carty
Derek Carty
Last 30d: 19-18-0 (+3.7u)
B.Robinson u18.5 Rush Att-125
1.25u
There is a value opportunity on Bijan Robinson's rush attempts prop. THE BLITZ is projecting him to record 16.40 rush attempts, while sportsbooks imply 20.04. The model believes there is a 73% chance he records fewer than 18.5 rush attempts, so there is some value on the under at -125. This play is good down to at least -173. Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Kendra Middleton
Kendra Middleton
Last 30d: 16-17-0 (+0.8u)
ATL +2.5+108
0.25u
TAN Pod Touchdown Show
TAN Pod Touchdown Show
Last 30d: 20-98-6 (-9.5u)
D.London Anytime TD Scorer Yes+140
0.71u
J.Watkins Anytime TD Scorer Yes+550
0.18u
Action Network Live!
Action Network Live!
Last 30d: 18-53-0 (-5.8u)
B.Robinson o28.5 Rec Yds-125
1u
B.Robinson 40+ Receiving Yards Yes+168
0.6u
B.Robinson 50+ Receiving Yards Yes+300
0.33u
B.Robinson 60+ Receiving Yards Yes+475
0.21u
B.Robinson 70+ Receiving Yards Yes+700
0.14u
B.Robinson 80+ Receiving Yards Yes+920
0.11u
B.Robinson 90+ Receiving Yards Yes+1340
0.07u
J.Watkins Anytime TD Scorer Yes+500
0.2u

49ers vs. Falcons Previews & Analysis

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    National Tight Ends Day TD Picks & Parlays

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    Oct 25, 2026 UTC
  • NFL Anytime Touchdown Machine: Live TD Odds & Trends article feature image

    NFL Anytime Touchdown Machine: Live TD Odds & Trends

    Evan Abrams•
    Oct 25, 2026 UTC
  • 49ers vs. Falcons: Desperation Spot for Dirty Birds article feature image

    49ers vs. Falcons: Desperation Spot for Dirty Birds

    Doug Kezirian•
    Oct 25, 2026 UTC
  • Week 7 Luck Rankings Dashboard: All Edges in One Place article feature image

    Week 7 Luck Rankings Dashboard: All Edges in One Place

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49ers vs. Falcons Props

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49ers vs. Falcons Public Betting Percentages

Away Logo

49ers

Public

61%

Bets%

39%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Falcons
2-40-32-10-12-3
49ers
4-22-21-02-22-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Falcons
4-22-12-11-03-2
49ers
3-32-21-02-21-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Falcons
2-4N/AN/A0-12-3
49ers
6-0N/AN/A4-02-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 18thCHIL 23-31+1.5 LO 51.5CHI -105
Oct 12thBALL 23-30-3 LO 44BAL -180
Oct 6th@NOW 45-24+1.5 WO 47.5ATL -105
Sep 25th@GBW 35-14+4.5 WO 43.5ATL +205
Sep 20thCARL 3-34+2.5 LU 43.5CAR +120

Falcons vs. 49ers Injury Updates

Falcons Injuries

  • Olamide Zaccheaus
    WR

    Zaccheaus is out with shoulder

    Out

  • Brian Robinson
    RB

    Robinson is out with hamstring

    Out

49ers Injuries

  • Mike Evans
    WR

    Evans is out with achilles

    Out

  • Demarcus Robinson
    WR

    Robinson is out with ankle

    Out

  • Deebo Samuel
    WR

    Samuel is out with hamstring

    Out

  • Jake Tonges
    TE

    Tonges is out with knee

    Out

  • De'Zhaun Stribling
    WR

    Stribling is out with ankle

    Out

Team Stats
150
Total Yards
73
20
Total Plays
15
7.5
Yards Per Play
4.9
75
YDS
36
6/7
Comps/Atts
5/6
8.5
YPA
6
0/0
TDs/INTs
0/0
1/7
Sacks/Yards
0/0
82
Rush Yards
37
12
Attempts
9
6.833
YPC
4.111
2
TDs
0

Turnovers

0
Fumbles Lost
0
0
Interceptions
0

Efficiency

1/1 100%
Redzone
0/1 0%
2/4 0%
3rd Down
1/3 0%
1/1 0%
4th Down
0/0 0%

First Downs

8
Total
4
4
Pass
2
4
Rush
2
0
Penalty
0
1/5
Penalties/Yards
1/5
10:52
Possession
9:50

49ers vs. Falcons Odds Comparison

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49ers at Falcons Team Totals

MatchupOverUnder
49ers
6-0
N/A
N/A
Falcons
2-4
N/A
N/A