MLB Betting Guide: Everything to Know to Bet on Baseball for 2022

MLB Betting Guide: Everything to Know to Bet on Baseball for 2022 article feature image

Jamie Sabau/Getty Images. Pictured: MLB Opening Day 2021

  • MLB Opening Day is here and we have everything you need to know to bet on baseball in 2022.
  • From how to bet to what to bet and everything in between, let this serve as your guide as the season gets underway.

It's finally here.

After a long offseason and a lockout that somehow seemed even longer, a full, 162-game Major League Baseball season begins today.

The Action Network has everything you could possibly need to prepare you for the new season, including tips on betting baseball, recommendations in the futures market for the 2022 season, and breakdowns and betting picks for all seven of today's game. Plus some neat prop betting options as well.


Daily Odds: Our live MLB odds page automatically refreshes with the best betting odds across the board each and every day.

Expert Projections: Senior betting analyst Sean Zerillo is the engine that runs our daily projections, helping you gain an edge before placing your bets.

The Action Network App: Download the app to track your bets, follow experts, shop for betting lines and so much more.

Payoff Pitch: The Action Network's newest betting podcast is chock full of preseason previews, and will come to you every Tuesday and Friday during the regular season with a breakdown of that day's slate. Subscribe, rate and review!

YouTube: Subscribe to the Action Network's YouTube channel, which will have daily betting picks and more all season long.

How to Bet on Baseball

Tips for Handicapping Baseball: Staff writer B.J. Cunningham offers this handy guide detailing his process for handicapping MLB games.

The Umpire Factor: Senior betting analyst Collin Wilson shows you how you can gain an edge when betting on baseball with the seemingly difficult element of projecting what umpires will do.

2022 Futures

Zerillo's MLB Mega-Preview: Zerillo breaks down all 30 teams to find value in the futures market, including win totals, divisional futures, World Series odds and more.

Staff Futures: The Action Network's betting analysts break down their favorite team-related future bets ahead of the start of the season.

Zerillo's Awards Breakdown: Zerillo gives out his favorite betting picks for MVP, Cy Young and Rookie of the Year.

MVP Futures: The Action Network's betting analysts give out their favorite picks for Most Valuable Player.

Cy Young Futures: The Action Network's betting analysts give out their favorite picks for this year's AL and NL Cy Young awards.

Rookie of the Year Futures: The Action Network's betting analysts give out their favorite picks for the top newcomers in both the American League and National League.

Stat Leaders: The Action Network's betting analysts look through a number of the stat leader futures and give out their favorite picks for home run leader, stolen base leader and more.

Zerillo's Player Props: Zerillo goes through the market for all the league leaders and gives out his favorite picks for a plethora of categories.

Make/Miss Playoffs: Senior editor Collin Whitchurch dives into the futures market to see if you can find value in Make Playoffs or Miss Playoffs wagers.

Undervalued Pitchers: Staff writer Anthony Dabbundo identifies 10 pitchers he believes will be undervalued by the betting market early on in the 2022 season.

Overvalued Pitchers: Conversely, Dabbundo also identifies 10 pitchers he believes the market will be too high on early in the 2022 season.

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Betting on Opening Day

Staff Best Bets: The Action Network's staff of betting analysts provide their favorite bets from Thursday's seven-game slate.

Brewers vs. Cubs (2:20 p.m. ET): Contributor D.J. James on if there's value on Milwaukee to get its NL Central defense off on the right foot in Chicago.

Mets vs. Nationals (4:05 p.m. ET): Contributor Mike Ianniello details whether or not Tylor Megill can get the job done for New York, which is already dealing with injuries to Jacob deGrom and Max Scherzer.

Guardians vs. Royals (4:10 p.m. ET): Two Cy Young winners at very different points in their careers take the mound in Kansas City. Contributor Doug Ziefel breaks down where the value lies.

Pirates vs. Cardinals (4:15 p.m. ET): St. Louis went on a remarkable late-season run last year. Will the magic carry over, or is there value on a Pittsburgh team once again expected to finish in the basement. Contributor Charlie DiSturco breaks it down.

Reds vs. Braves (7:20 p.m. ET): Contributor Jules Posner breaks down if the Braves — without franchise icon Freddie Freeman — will get their World Series defense off to a good start against Cincinnati.

Astros vs. Angels (9:38 p.m. ET): Shohei Ohtani takes the mound against the defending American League champions on Opening Day. Contributor Kenny Ducey on how to bet this heavyweight AL West clash.

Padres vs. Diamondbacks (9:40 p.m. ET): A pair of aging aces take the mound as Yu Darvish and San Diego face Madison Bumgarner and Arizona. Can playoff hopeful San Diego get the job done as a favorite? Contributor Nick Shlain breaks it down.

Player Props: Betting on games isn't the only way to find value. Contributor Tanner McGrath goes through Thursday's entire slate and identifies three player props that have value.

PrizePicks Props: Don't live in a state with legal online sports betting? PrizePicks has you covered. Contributor Tony Sartori gives out five picks to build out the best prop slate you can on Opening Day.

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