Indiana vs. Ohio State Odds & Betting Predictions - December 7, 2025
Indiana at Ohio State
1:00 am • FOXIndiana at Ohio State Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Indiana 7-1 | +6 | +3.5-112 | o45.5-110 | +150 |
 Ohio State 6-1 | u49.5 | -3.5-108 | u45.5-110 | -185 |
Lucas Oil StadiumIndianapolis
Indiana vs. Ohio State Expert Picks
YBK Picks.com
Last 30d: 45-46-2 (-6.2u)
IU +4.5-105
2.86u
Vegas Refund
Last 30d: 32-43-2 (-15.7u)
IU +4.5-110
1u
Collin Wilson
Last 30d: 90-74-2 (+5.7u)
IU +6-110
1u
Project Ohio State -4
Stuck 🚨
Last 30d: 69-76-2 (+2.4u)
IU +4.5-115
0.3u
Pretty close to market. Smaller gut. https://www.actionnetwork.com/ncaaf/college-football-picks-expert-conference-championship-best-bets-ohio-state-vs-indiana-alabama-vs-georgia
Mike McNamara
Last 30d: 85-74-2 (+4.2u)
IU +170
4.42u
Sean Zerillo
Last 30d: 142-140-7 (+2.0u)
IU +4.5-110
0.25u
Kody Malstrom
Last 30d: 72-60-2 (+2.0u)
IU +6-110
0.5u
Proj +3.9
Anthony Dabbundo
Last 30d: 48-66-0 (-19.8u)
Under 47.5-110
1u
Doug Ziefel
Last 30d: 427-417-9 (+35.7u)
Under 48-110
0.5u
F.Mendoza o15.5 Rush Yds-115
0.58u
E.Sarratt u59.5 Rec Yds-115
0.5u
Jeremiah Rose
Last 30d: 58-65-3 (-2.0u)
OSU -170 (Live)
0.25u
Duck
Last 30d: 105-79-2 (+10.9u)
Under 24.5 (1H)-132
1u
OSU -125 (Live)
1.25u
Ryan Minion
Last 30d: 249-234-3 (+27.2u)
IU +6-110
$3.00
J.Smith o5.5 Recs-130
$1.00
J.Smith o73.5 Rec Yds-115
$1.00
Picks Office
Last 30d: 0-0-0 (+0.0u)
IU +4.5-110
0.91u
Join Discord: https://discord.gg/NcyhmJVXPe
Under 47.5-110
0.91u
Join Discord: https://discord.gg/NcyhmJVXPe
Sandy Plashkes
Last 30d: 115-115-4 (+23.6u)
IU +4-110
2u
The Degenerates
Last 30d: 61-58-2 (-0.7u)
OSU -4-110
1.1u
Mike Calabrese
Last 30d: 44-59-0 (+1.8u)
IU +165
1.65u
IU +142 (1H)
1u
Lock & Cash
Last 30d: 7-8-0 (-0.1u)
OSU -4-110
2u
Dan Gaspar
Last 30d: 38-33-3 (+0.6u)
F.Mendoza u22.5 Rush Yds-115
1u
R.Hemby o3.5 Rec Yds-115
1u
B.Inniss o14.5 Rec Yds-115
1.15u
K.Black o32.5 Rush Yds-115
1u
Big Bets On Campus (CFB)
Last 30d: 55-65-2 (-10.8u)
IU +6-110
0.91u
@Stuckey2 @_Collin1 https://myaction.app/SXl6WrC0QYb
Brandon Kravitz
Last 30d: 60-61-2 (+8.1u)
IU +4+100
1u
IU +4+100
1u
Adding to original position
IU +155
0.78u
Colby Marchio
Last 30d: 1-1-0 (-0.1u)
OSU -3.5-115
1.25u
Mjaybrod
Last 30d: 58-79-1 (-22.3u)
OSU u26.5-110
0.91u
Sorry Biev
OSU u26.5-105
0.95u
Another
Cam Is Money
Last 30d: 0-0-0 (+0.0u)
IU +4-110
0.91u
Road to CFB
Last 30d: 33-21-0 (+8.7u)
OSU o13.5 (1H)-110
1.1u
Invisible Insider
Last 30d: 0-0-0 (+0.0u)
OSU -4-110
0.75u
Am I falling for it? They’re so much better.
💰🦡 Jake
Last 30d: 101-111-1 (+21.9u)
IU +145 (1H)
0.75u
John Feltman
Last 30d: 108-64-1 (+27.5u)
IU +4-110
5u
Sir Lockselot
Last 30d: 18-40-0 (+1.2u)
OSU -3.5-112
2u
📚Player Profit
New Owner
Last 30d: 0-0-0 (+0.0u)
IU +7.5 (Live)-125
2u
The Propfessor
Last 30d: 0-0-0 (+0.0u)
J.Smith o5.5 Recs-125
0.8u
Jeremiah looks to step up in the big stage once again, this time, in his first Big 10 Championship.
Smith this season has gone over this number in 7/11 games overall, averaging 6.5 per game. When he runs 20+ routes, he is over in 7/9 games, averaging 8.8 targets per game.
He will now faces Indiana in the battle between the undefeateds, and #1 and #2 in the nation.
Opposing WRs have been able to find success against this defense most of the season. Smith will be finding his spots all game long and I love this spot for him to rack up the grabs.
Indiana’s run defense is very elite, ranking top 5 in the nation in success rate, stuff rate, and line yards on the season. Expecting the OSU offense to lean on Julian Sayin and the passing game a lot more than usual in this one.
Indiana also runs a ton of zone coverage. Jeremiah feasts against zone and is OSU’s best WR by far against it, with a 0.32 TPRR against zone coverage on the year.
Last season, in the postseason, we saw Smith have 7+ targets in 3/4 games. Love for this to continue for him tomorrow…
Roger Goodell
Last 30d: 0-0-0 (+0.0u)
OSU -4-110
1u
OSU -3.5-112
1u
THROWING ANOTHER UNIT DOWN. -3.5 ON DK I CAN’T RESIST
Indiana vs. Ohio State Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Indiana vs. Ohio State Public Betting Percentages
Betting Trends
- Ohio State are 5-0 in their last 5 games.
- Ohio State are 3-2 in their last 5 games against the spread
- Ohio State are 3-0 in their road games against the spread
- The totals have gone OVER in 4 of Ohio State' last 5 games
- The totals have gone OVER in 4 of Ohio State' 4 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 5-2 | 2-2 | 3-0 | 2-2 | 1-0 |
| 1-7 | 0-5 | 1-2 | 1-3 | 0-1 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 4-3 | 4-0 | 0-3 | 2-2 | 0-1 |
| 3-5 | 2-3 | 1-2 | 2-2 | 0-1 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 6-1 | N/A | N/A | 4-0 | 0-1 |
| 7-1 | N/A | N/A | 4-0 | 0-1 |
Last 5 Matchups
Team Stats
222
YDS
264
15/23
Comps/Atts
22/30
9.652173913043478
YPA
8.8
1/1
TDs/INTs
1/1
3/10
Sacks/Yards
5/29
5/49
Penalties/Yards
2/20
Indiana vs. Ohio State Odds Comparison
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Indiana at Ohio State Team Totals
MatchupOverUnder | ||
|---|---|---|
Indiana 7-1 | N/A | N/A |
Ohio State 6-1 | N/A | N/A |