Indiana vs. Ohio State Odds & Betting Predictions - December 7, 2025
Indiana at Ohio State
1:00 am • FOXIndiana at Ohio State Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Indiana 16-0 | +6 | +3.5-112 | o45.5-110 | +150 |
Ohio State 12-2 | u49.5 | -3.5-108 | u45.5-110 | -185 |

Lucas Oil StadiumIndianapolis
Indiana vs. Ohio State Expert Picks
Duck
Last 30d: 93-78-0 (+5.0u)
OSU -125 (Live)
1.25u
Boomer Betz
Last 30d: 79-78-2 (-3.3u)
IU +7.5 (Live)-125
2u
Jeremiah Rose
Last 30d: 22-11-0 (+12.1u)
OSU -170 (Live)
0.25u
Sir Lockselot
Last 30d: 23-62-1 (-28.4u)
OSU -3.5-112
2u
📚Player Profit
Brandon Kravitz
Last 30d: 75-77-1 (+7.7u)
IU +155
0.78u
IU +4+100
1u
Adding to original position
YBK Picks.com
Last 30d: 10-9-0 (+1.9u)
IU +4.5-105
2.86u
Lock & Cash
Last 30d: 16-19-0 (-4.2u)
OSU -4-110
2u
Picks Office
Last 30d: 230-151-2 (+62.6u)
Under 47.5-110
0.91u
Join Discord: https://discord.gg/NcyhmJVXPe
Mjaybrod
Last 30d: 59-44-0 (+22.2u)
OSU u26.5-105
0.95u
Another
Stuck 🚨
Last 30d: 58-56-1 (+0.2u)
IU +4.5-115
0.3u
Pretty close to market. Smaller gut. https://www.actionnetwork.com/ncaaf/college-football-picks-expert-conference-championship-best-bets-ohio-state-vs-indiana-alabama-vs-georgia
Mike Calabrese
Last 30d: 56-51-2 (+8.6u)
IU +142 (1H)
1u
Vegas Refund
Last 30d: 36-24-0 (+10.1u)
IU +4.5-110
1u
Mjaybrod
Last 30d: 59-44-0 (+22.2u)
OSU u26.5-110
0.91u
Sorry Biev
Mike Calabrese
Last 30d: 56-51-2 (+8.6u)
IU +165
1.65u
The Degenerates
Last 30d: 107-103-11 (-7.0u)
OSU -4-110
1.1u

Sean Zerillo
Last 30d: 47-58-0 (-1.1u)
IU +4.5-110
0.25u
Ryan Minion
Last 30d: 222-231-3 (+53.5u)
J.Smith o5.5 Recs-130
$1.00
J.Smith o73.5 Rec Yds-115
$1.00
Roger Goodell
Last 30d: 1-7-0 (-6.6u)
OSU -3.5-112
1u
THROWING ANOTHER UNIT DOWN. -3.5 ON DK I CAN’T RESIST
Invisible Insider
Last 30d: 0-3-0 (-3.1u)
OSU -4-110
0.75u
Am I falling for it? They’re so much better.
The Propfessor
Last 30d: 56-49-0 (+12.1u)
J.Smith o5.5 Recs-125
0.8u
Jeremiah looks to step up in the big stage once again, this time, in his first Big 10 Championship.
Smith this season has gone over this number in 7/11 games overall, averaging 6.5 per game. When he runs 20+ routes, he is over in 7/9 games, averaging 8.8 targets per game.
He will now faces Indiana in the battle between the undefeateds, and #1 and #2 in the nation.
Opposing WRs have been able to find success against this defense most of the season. Smith will be finding his spots all game long and I love this spot for him to rack up the grabs.
Indiana’s run defense is very elite, ranking top 5 in the nation in success rate, stuff rate, and line yards on the season. Expecting the OSU offense to lean on Julian Sayin and the passing game a lot more than usual in this one.
Indiana also runs a ton of zone coverage. Jeremiah feasts against zone and is OSU’s best WR by far against it, with a 0.32 TPRR against zone coverage on the year.
Last season, in the postseason, we saw Smith have 7+ targets in 3/4 games. Love for this to continue for him tomorrow…
Cam Is Money
Last 30d: 56-66-1 (-14.0u)
IU +4-110
0.91u
Brandon Kravitz
Last 30d: 75-77-1 (+7.7u)
IU +4+100
1u
Big Bets On Campus (CFB)
Last 30d: 5-3-1 (+1.8u)
IU +6-110
0.91u
@Stuckey2 @_Collin1 https://myaction.app/SXl6WrC0QYb
Dan Gaspar
Last 30d: 0-0-0 (+0.0u)
K.Black o32.5 Rush Yds-115
1u
B.Inniss o14.5 Rec Yds-115
1.15u
R.Hemby o3.5 Rec Yds-115
1u
Sandy Plashkes
Last 30d: 85-79-6 (-3.9u)
IU +4-110
2u
Picks Office
Last 30d: 230-151-2 (+62.6u)
IU +4.5-110
0.91u
Join Discord: https://discord.gg/NcyhmJVXPe
John Feltman
Last 30d: 57-52-4 (-4.0u)
IU +4-110
5u
Roger Goodell
Last 30d: 1-7-0 (-6.6u)
OSU -4-110
1u
💰🦡 Jake
Last 30d: 102-103-3 (+25.7u)
IU +145 (1H)
0.75u
Dan Gaspar
Last 30d: 0-0-0 (+0.0u)
F.Mendoza u22.5 Rush Yds-115
1u
Doug Ziefel
Last 30d: 126-131-1 (+5.9u)
E.Sarratt u59.5 Rec Yds-115
0.5u
F.Mendoza o15.5 Rush Yds-115
0.58u
Under 48-110
0.5u
Mike McNamara
Last 30d: 64-83-1 (-2.0u)
IU +170
4.42u
Duck
Last 30d: 93-78-0 (+5.0u)
Under 24.5 (1H)-132
1u
Road to CFB
Last 30d: 2-3-0 (-0.3u)
OSU o13.5 (1H)-110
1.1u
Ryan Minion
Last 30d: 222-231-3 (+53.5u)
IU +6-110
$3.00
Collin Wilson
Last 30d: 4-4-1 (+1.2u)
IU +6-110
1u
Project Ohio State -4
Indiana vs. Ohio State Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Indiana vs. Ohio State Public Betting Percentages
Betting Trends
- Ohio State are 5-0 in their last 5 games.
- Ohio State are 4-1 in their last 5 games against the spread
- Ohio State are 4-1 in their road games against the spread
- The totals have gone OVER in 2 of Ohio State' last 5 games
- The totals have gone OVER in 4 of Ohio State' 7 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 10-3 | 6-1 | 4-1 | 9-3 | N/A | |
| 8-5 | 4-3 | 3-2 | 5-5 | 2-0 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 4-9 | 4-3 | 0-5 | 3-9 | N/A | |
| 8-5 | 5-2 | 3-2 | 7-3 | 0-2 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 12-1 | N/A | N/A | 11-1 | N/A | |
| 13-0 | N/A | N/A | 10-0 | 2-0 |
Last 5 Matchups
Team Stats
222
YDS
264
15/23
Comps/Atts
22/30
9.652173913043478
YPA
8.8
1/1
TDs/INTs
1/1
3/10
Sacks/Yards
5/29
5/49
Penalties/Yards
2/20
Indiana vs. Ohio State Odds Comparison
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Indiana at Ohio State Team Totals
MatchupOverUnder | ||
|---|---|---|
Indiana 16-0 | N/A | N/A |
Ohio State 12-2 | N/A | N/A |






