Patriots vs. Bills Odds & Betting Predictions - October 4, 2026
Patriots at Bills
5:00 pm • CBSPatriots at Bills Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Patriots 4-3 | +3 | +7-113 | o49.5-106 | +272 |
Bills 5-1 | u49.5 | -7-106 | u49.5-111 | -350 |

Highmark StadiumOrchard Park
Patriots vs. Bills Expert Picks
Vegas Refund
Last 30d: 24-38-2 (-18.3u)
BUF -6.5-120
1.2u
Mike McNamara
Last 30d: 72-68-2 (+1.2u)
BUF -7-110
0.4u
Sean Koerner🔮
Last 30d: 49-61-0 (+1.8u)
D.Kincaid u4.5 Recs-122
0.5u
This reminds me a bit of the Dalton Schultz under last week. I know Kincaid is a beast, he’s currently top 5 in my fantasy rankings, but he’s much more of a big-play threat this year than a Tyler Warren type who might catch 9 balls for 50 yards. Kincaid could absolutely go 4/90/2 here, which would be great for fantasy and still cash this under.
Despite seeing mostly downfield targets, Kincaid has an 82% catch rate, a career high and about 15% above expected, so there’s some regression coming there. He’s also historically been less efficient against man coverage. The Pats may play a little less man with Christian Gonzalez out, but that probably opens things up more for DJ Moore and the other WRs too, which isn’t necessarily helping Kincaid’s target volume.
New England hasn’t faced any TEs of Kincaid’s caliber yet, but they’ve generally held the position below expectation. I have him closer to 4.1 receptions with around a 60% chance to stay under 4.5. Again, he can still do a TON of damage on 3-4 catches.
Anthony Dabbundo
Last 30d: 44-59-0 (-17.2u)
BUF -6.5-115
1.15u
Under 48.5 (Live)-110
1.1u
From Ringer betting column - never logged
Doug Ziefel
Last 30d: 374-383-8 (+25.8u)
NE +7-115
0.5u
D.Maye u0.5 Int+120
0.42u
H.Henry u3.5 Recs-120
0.6u
J.Cook o1.5 Recs+100
0.5u
R.Doubs o3.5 Recs+140
0.5u
Jeremiah Rose
Last 30d: 45-55-2 (-2.8u)
BUF -6.5-120
0.3u
Ryan Minion
Last 30d: 231-220-1 (+22.5u)
NE +7-115
$1.00
R.Doubs o39.5 Rec Yds-113
$2.65
R.Doubs o3.5 Recs+120
$1.20
Collin Whitchurch
Last 30d: 101-134-3 (-0.5u)
D.Kincaid u4.5 Recs-122
0.5u
T.Henderson Anytime TD Scorer Yes+274
0.25u
Sandy Plashkes
Last 30d: 101-105-4 (+12.2u)
NE +7-120
1.5u
MJC
Last 30d: 8-6-0 (+7.3u)
J.Cook Anytime TD Scorer Yes-108
1u
Played on NoVig
J.Cook 2+ TDs Yes+470
0.25u
The Degenerates
Last 30d: 49-50-2 (-4.6u)
BUF -6.5 (Live)-112
1.12u
Kyle Murray
Last 30d: 151-135-9 (+20.4u)
R.Stevenson o2.5 Recs-114
1u
RoyalsProps
Last 30d: 33-43-2 (-15.7u)
D.Kincaid o50.5 Rec Yds-114
1.14u
Frank Ammirante
Last 30d: 99-90-0 (-4.3u)
D.Maye u234.5 Pass Yds-113
1.13u
BUF -6.5-115
1.15u
Nick Giffen
Last 30d: 46-115-0 (+3.2u)
NE +7-115
0.5u
Allan Lem
Last 30d: 45-30-1 (+3.3u)
D.Kincaid u4.5 Recs-146
0.5u
Tailing @The_Oddsmaker
Mjaybrod
Last 30d: 55-80-1 (-26.1u)
NE o20.5-114
0.88u
Adam Kaufman
Last 30d: 317-298-11 (-18.0u)
NE +7-115
1u
Under 24.5 (1H)-115
0.25u
NE u10.5 (1H)-170
0.25u
NE u20.5-113
0.5u
BUF -2.5 (2Q)-115
0.22u
💰🦡 Jake
Last 30d: 88-105-1 (+12.1u)
Under 49.5-110
1.65u
Charlie DiSturco
Last 30d: 108-196-1 (+11.8u)
Over 49.5-105
0.5u
K.Shakir o35.5 Rec Yds-111
0.5u
Kendra Middleton
Last 30d: 15-17-0 (+0.5u)
Under 48.5-102
0.5u
TAN Pod Touchdown Show
Last 30d: 20-96-6 (-8.9u)
D.Maye Anytime TD Scorer Yes+500
0.2u
J.Allen 2+ TDs Yes+600
0.17u
Kev Mahserejian
Last 30d: 14-18-0 (-1.0u)
BUF -6.5-115
1u
Action Network Live!
Last 30d: 18-52-0 (-5.4u)
A.Borregales o5.5 Kicking Pts-118
1u
Patriots vs. Bills Previews & Analysis
Patriots vs. Bills Props
Prop Projections
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Prop Odds Comparison
Line Movement Tracker
Patriots vs. Bills Public Betting Percentages
Betting Trends
- Bills are 4-1 in their last 5 games.
- Bills are 3-2 in their last 5 games against the spread
- Bills are 2-1 in their road games against the spread
- The totals have gone OVER in 4 of Bills' last 5 games
- The totals have gone OVER in 2 of Bills' 3 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Bills vs. Patriots Injury Updates

Bills Injuries

Patriots Injuries
- Mack HollinsWR
Hollins is out with calf
Out
- Romeo DoubsWR
Doubs is out with shoulder
Out
Team Stats
Patriots vs. Bills Odds Comparison
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Patriots at Bills Team Totals
MatchupOverUnder | ||
|---|---|---|
Patriots 4-3 | N/A | N/A |
Bills 5-1 | N/A | N/A |




