The NBA regular season is back with a relatively light slate of games on Wednesday night, with a total of only two matchups scheduled for today, with Cavaliers vs. Bulls and Grizzlies vs. Timberwolves both set to tipoff at 8:00 p.m. ET.
Our staff of basketball betting experts dug into the latest odds and identified a pair of NBA picks for both of tonight's matchups.
Continue below for our NBA picks, odds, props, and predictions for Wednesday, December 17.
NBA Picks, Odds, Props, Predictions: Wednesday, December 17
| Game | Time (ET) | Pick |
|---|---|---|
  | 8 p.m. | |
  | 8 p.m. | |
| 8 p.m. | |
| 8 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NBA Odds page, which automatically surfaces the best lines for every game. | ||
Grizzlies vs. Timberwolves
By Joe Dellera
Anthony Edwards has missed the Wolves’ last two games with a foot injury, but I’ll back him assuming he plays tonight.
He’s now had nearly 10 days off, and in his last game dropped 40 points against the Suns.
Edwards averages 28.6 points per game, and has cleared this 27.5 line in 9-of-14 games.
He’s played well against the Grizzlies as well. In his last five games against Memphis, he’s scored 44, 32, 15, 34, and 28.
The Grizzlies play at a relatively fast pace, and they’ve been lit up by a few guards recently, including Keyonte George, De’Aaron Fox, and Jamal Murray.
If Ant sits, then we just void, but I figure he plays and should be fresh for this game.
Pick: Anthony Edwards Over 27.5 Points (-110)
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Cavaliers vs. Bulls
Both teams are in rough shape right now; two of the worst spread differential teams over the past two weeks according to Cleaning the Glass.
Strong signal to take the home team catching points, especially with Mobley still missing in action for Cleveland.
He hasn’t been great this year, but the Cavaliers don't have a direct defensive replacement with him out of the lineup, and Chicago can score.
The Bulls are also 4-1 ATS this season as home underdogs.
Pick: Bulls +5 (-110)
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Grizzlies vs. Timberwolves
By Bet Labs
The NBA system titled "Contrarian Overs, Good Road Teams" in totals betting is built on the idea that strong traveling teams can drive pace and scoring in matchups where the market leans too heavily toward the under.
By focusing on regular season games outside of division play, the system avoids slower rivalry environments and taps into contests that tend to be more open and less physical.
It targets overs specifically when the betting public and money trends show a clear lean toward the under, creating a contrarian opportunity where expectations are suppressed but conditions for scoring remain strong.
The away team must be early enough in its season to still carry energy and identity, and it must also be coming off a decisive win, a signal that its offense and confidence are functioning at a high level.
When these elements align, strong road teams often set the tone, push pace, and elevate scoring beyond market expectations, making the over more attractive precisely when it is being overlooked.
Pick: Over 230.5 (-110)
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Cavaliers vs. Bulls
By Kyle Murray
Tyson has cleared this number in six of his last seven games, and seven of his last nine, as he continues to benefit from some injuries in this Cleveland rotation.
Evan Mobley and Sam Merrill will miss this game once again, and we have still yet to see Max Strus this season.
As a result, Tyson projects for 31-32 minutes.
In that amount of time, I have him projected to clear this number on points alone (16.6), while also adding 2.4 assists.
Pick: Jaylon Tyson Over 14.5 Points & Assists (-120)
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