Week 6 continues with a few huge matchups in the afternoon slate, headlined by Texas playing Florida in The Swamp.
Check out our college football odds and best bets for Saturday afternoon's slate.
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College Football Best Bets
The team logos in the table below represent each of the matchups that our college football betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 3:30 p.m. | |
  | 3 p.m. | |
| 3:30 p.m. | |
  | 4 p.m. | |
 | Afternoon | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NCAAF Odds page, which automatically surfaces the best lines for every game. | ||
Collin's Card: Afternoon Best Bet
There was no progress for the Florida offense in a loss to Miami, as quarterback DJ Lagway was leashed with short routes and three drops by his targets.
The inside zone rushing attack needed every bit of Jadan Baugh's four yards after first contact, as the offensive line sits outside the top 40 nationally in Line Yards and outside the top 80 in Stuff Rate.
Texas has posted an average Defensive Success Rate against inside zone concepts, but passing attempts from Lagway into the Longhorns' nickel defense could be troublesome.
Florida has averaged just five offensive possessions per game when it comes to crossing the opponent's 40-yard line.
Conversely, the outside zone and counter concepts called by head coach Steve Sarkisian should help Texas capitalize on scoring opportunities.
The Longhorns have a minimum 61% Success Rate on those rushing attempts, concepts that Florida has posted just a 44% Success Rate in defending.
Texas hasn't had problems creating scoring opportunities. The issues have stemmed from an inability to put points on the board under head coach Steve Sarkisian.
The Florida defense has been excellent when pinned against the goal line, ranking 25th in Finishing Drives allowed. The Gators have faced only 10 opponent red-zone attempts, highlighting the strength of a defense that has allowed 18 opponent possessions to cross the 40-yard line.
Between Florida's defense stiffening, Texas' inefficiency in scoring opportunities and a limited Florida offense, there could be several possessions ending in a field-goal attempt.
These defenses have been elite in the opening quarter of the game, as Texas hasn't allowed a single point in the first 15 minutes of any game.
Florida has also limited opponents early, allowing only a Miami touchdown as the only first-quarter points this season against the Gators.
Read Collin's entire Texas-Florida breakdown and more in his full Week 6 column:
Pick: 1H Under 21 (-120) or Better
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Stuckey's Spots: Afternoon Best Bet
By Stuckey
Oklahoma State is an absolute mess. Its opponent-adjusted metrics on both sides of the ball almost appear to be a mistake. This is the worst power conference team by a magnificent margin.
How bad is it from a power ratings perspective? As of right now, I'd have lowly Western Michigan favored on a neutral field over the Pokes, who recently got dominated on their home field by Tulsa.
There's nothing to like about this team. The quarterback play is putrid behind an offensive line missing its best player, and the defense can't stop a nosebleed.
So, is this the bottom? Maybe not.
After firing head coach Mike Gundy last week, Oklahoma State fired defensive coordinator Todd Grantham on Sunday.
So, who will take over as the interim in his place? Clint Bowen, whom Gundy brought in as an offensive quality control coach in the offseason after Bowen spent the past four years at the high school level.
I also wouldn't be surprised to see a few more players enter the portal.
Oklahoma State lacks direction on defense, while its offense operates with tempo, showing no discernible strengths. That's a recipe for a complete blowout in the desert against what should be an angry Arizona bunch coming off a blowout loss in Ames.
The Wildcats got burned by allowing too many explosive passing plays against the Cyclones, who also exploited them over the middle of the field.
Well, that shouldn't be much of an issue against quarterback Zane Flores, who really struggles to throw between the hashes and has completed just three of his 21 (14.3%) deep balls this season.
Meanwhile, Arizona should find success doing whatever it chooses while on offense.
Last week, the wide receivers struggled to get separation against the Iowa State secondary. That won't be an issue this week. And the ground game should really get going on early downs, making life much easier for quarterback Noah Fifita.
Arizona's special teams are a bit of a mess at the moment, but that shouldn't matter in this one.
Give me the Wildcats to bounce back in a big way by at least three touchdowns against the corpse of Oklahoma State.
Check out all of Stuckey's Week 6 situational spots here:
Pick: Arizona -20 or Better
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Ziefel's Top Player Prop
By Doug Ziefel
The Gators have gotten support from the market throughout the week, and a tight matchup lends itself to a more pass-heavy scheme from the Longhorns.
Texas runs the ball at the 28th highest rate nationally, and quarterback Arch Manning is a part of that. Still, we should see Manning flash his pocket prowess in this matchup as the Gators have struggled to generate pressure, ranking 126th nationally in sack rate.
Meanwhile, Manning got his confidence back two weeks ago, going 18 for 21 passing against Sam Houston State.
With two weeks to prepare for this matchup, look for Texas to put the ball in the hands of its star quarterback in an effort to pass this big road test.
Pick: Arch Manning Over 25.5 Pass Attempts (-120, bet365)
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Our Featured Bet Labs System
This game triggered one of our Action Labs PRO betting systems, powered by Evan Abrams.
In non-conference games where the spread is over four touchdowns and the total is lower than 55, Overs have hit at a nearly 60% clip over the past two decades.
Typically, the stronger, often Power Conference team is too much for the lower-level, often Group of 5 team, and the score quickly runs up.
Even without John Mateer, I suspect the Sooners pour it on against the pitiful Golden Flashes.
Pick: Over 53.5 (-110, bet365)
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Breese's Full Action App Card
Need more picks for Week 6? It's always wise to see what our guy Breese is betting on each week!
Additionally, if you haven't already, make sure you download the free award-winning Action Network App to track all your bets and tail all of your favorite experts:
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