Colts vs. Chiefs Odds & Betting Predictions - November 23, 2025

Colts at Chiefs

6:00 pm • CBS

Indianapolis Colts

@

Kansas City Chiefs

MatchupOpenSpreadTotalMoneyline
Colts 7-1	N/A	N/A	N/A
Chiefs 5-3	N/A	N/A	N/A

location pin

Sunday 6:00 p.m.

November 23, 2025

GEHA Field at Arrowhead StadiumKansas City

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NFL Public Betting

Chiefs are 3-2 in their last 5 games.
Chiefs are 3-2 in their last 5 games against the spread
Chiefs are 1-1 in their road games against the spread
The totals have gone OVER in 3 of Chiefs' last 5 games
The totals have gone OVER in 1 of Chiefs' 5 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Chiefs	5-3	4-1	1-1	4-2	1-1
Colts	6-2	4-1	2-1	4-1	2-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Chiefs	3-5	1-4	1-1	2-4	1-1
Colts	5-3	3-2	2-1	3-2	2-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Chiefs	5-3	N/A	N/A	4-2	1-1
Colts	7-1	N/A	N/A	5-0	2-1

date	opponent	score	spread	over/under	moneyline
Oct 28th	WAS	W 28-7	-10.5 W	U 48	KC -590
Oct 19th	LV	W 31-0	-13.5 W	U 44.5	KC -850
Oct 13th	DET	W 30-17	-2.5 W	U 51.5	KC -150
Oct 7th	@JAC	L 28-31	-3.5 L	O 45.5	JAC -202
Sep 28th	BAL	W 37-20	+2.5 W	O 48.5	KC +125

Isiah Pacheco
RB
Pacheco is doubtful with knee
Doubtful

Esa Pole
T
Pole is out with ankle
Out

See more NFL Injuries

passing yards
Patrick Mahomes
2099
pyds
passing touchdowns
Patrick Mahomes
17
ptd
rushing yards
Isiah Pacheco
329
ryds
rushing touchdowns
Patrick Mahomes
4
rtd

	Starter	2ND	3RD	4TH
QB	Patrick Mahomes	Gardner Minshew	Chris Oladokun
RB	Isiah Pacheco	Kareem Hunt	Elijah Mitchell	Brashard Smith
WR	Rashee Rice	Nikko Remigio
TE	Travis Kelce	Noah Gray	Jared Wiley	Robert Tonyan	Tre Watson	Jake Briningstool
LT	Josh Simmons	Wanya Morris	Esa Pole
LG	Kingsley Suamataia	Mike Caliendo
C	Creed Humphrey	Hunter Nourzad
RG	Trey Smith	C.J. Hanson	Ethan Driskell
RT	Jawaan Taylor	Jaylon Moore	Chukwuebuka Godrick
LDE	George Karlaftis	Charles Omenihu	Malik Herring
RDE	Mike Danna	Ashton Gillotte
WLB	Drue Tranquill	Jeffrey Bassa	Cooper McDonald
MLB	Nick Bolton	Jack Cochrane	Brandon George
LCB	Jaylen Watson	Nohl Williams
SS	Jaden Hicks	Chamarri Conner
FS	Bryan Cook	Mike Edwards
RCB	Kristian Fulton	Nazeeh Johnson	Joshua Williams
P	Matt Araiza
H	Matt Araiza
PR	Nikko Remigio	Brashard Smith
KR	Nikko Remigio	Brashard Smith
LS	James Winchester
ROLB	Leo Chenal	Cole Christiansen
NT	Chris Jones	Jerry Tillery
LWR	Xavier Worthy	JuJu Smith-Schuster	Jason Brownlee	Jimmy Holiday
FB	Carson Steele
NB	Trent McDuffie	Kevin Knowles	Chris Roland-Wallace	Melvin Smith
K	Harrison Butker
RWR	Marquise Brown	Jalen Royals	Tyquan Thornton
DT	Omarr Norman-Lott	Marlon Tuipulotu

Total

Passing

2007

YDS

2014

174/248

Comps/Atts

189/282

8.351

YPA

7.443

13/3

TDs/INTs

17/4

9/64

Sacks/Yards

14/85

Rushing

1075

Rush Yards

1012

214

Attempts

225

5.023

YPC

4.498

18

TDs

9

Turnovers

Fumbles Lost

3

Interceptions

4

Efficiency

26/38 68.42%

Redzone

24/34 70.59%

39/86 0%

3rd Down

44/100 0%

10/12 0%

4th Down

14/17 0%

First Downs

186

Total

189

104

Pass

107

66

Rush

70

16

Penalty

12

Misc

/

Penalties/Yards

/

Possession

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MatchupOverUnder
Colts 7-1	N/A	N/A
Chiefs 5-3	N/A	N/A