Seahawks vs. Cardinals Odds & Betting Predictions - September 26, 2025
Seahawks at Cardinals
12:15 am • Amazon Prime VideoSeahawks at Cardinals Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Seahawks 2-1 | +2.5 | +1.5-115 | o43.5-110 | -103 |
 Cardinals 2-1 | u46.5 | -1.5-105 | u43.5-110 | -116 |
State Farm StadiumGlendale
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Seahawks vs. Cardinals Expert Picks
FTN Fantasy
Last 30d: 70-89-0 (-27.1u)
SEA +1.5-110
1u
SEA +107
1u
Seahawks vs. Cardinals Previews & Analysis
Seahawks vs. Cardinals Props
Prop Projections
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Prop Odds Comparison
Line Movement Tracker
Seahawks vs. Cardinals Public Betting Percentages
Betting Trends
- Cardinals are 2-1 in their last 5 games.
- Cardinals are 2-1 in their last 5 games against the spread
- Cardinals are 2-0 in their road games against the spread
- The totals have gone OVER in 1 of Cardinals' last 3 games
- The totals have gone OVER in 1 of Cardinals' 1 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Seahawks vs. Cardinals Injury Updates
Seahawks Injuries
- Uchenna NwosuLB
Nwosu is out with knee
Out
- Zach CharbonnetRB
Charbonnet is out with foot
Out
Cardinals Injuries
- Will HernandezOL
Hernandez is out with knee
Out
- Owen PappoeLB
Pappoe is questionable with quad
Questionable
- Dante StillsDE
Stills is questionable with heel
Questionable
Player Stats
- passing yards
Kyler Murray542pyds - passing touchdownsKyler Murray4ptd
- rushing yards
Trey Benson125ryds - rushing touchdowns
James Conner1rtd
Depth Charts
| Starter | 2ND | 3RD | 4TH | ||
|---|---|---|---|---|---|
| QB | Kyler Murray | Jacoby Brissett | |||
| RB | James Conner | Trey Benson | Emari Demercado | Michael Carter | Bam Knight |
| WR | Greg Dortch | Zay Jones | Andre Baccellia | ||
| TE | Trey McBride | Tip Reiman | Elijah Higgins | Travis Vokolek | Josiah Deguara |
| LT | Paris Johnson | Kelvin Beachum | Jake Curhan | ||
| LG | Evan Brown | Nick Leverett | |||
| C | Hjalte Froholdt | Jon Gaines | |||
| RG | Isaiah Adams | Will Hernandez | Hayden Conner | ||
| RT | Jonah Williams | Christian Jones | Josh Fryar | Jeremiah Byers | |
| LDE | Calais Campbell | Walter Nolen | L.J. Collier | Anthony Goodlow | |
| RDE | Darius Robinson | Justin Jones | Bilal Nichols | ||
| WLB | Akeem Davis-Gaither | Owen Pappoe | |||
| MLB | Mack Wilson | Cody Simon | J.J. Russell | ||
| LCB | Will Johnson | Elijah Jones | |||
| SS | Jalen Thompson | Dadrion Taylor-Demerson | |||
| FS | Budda Baker | Joey Blount | Kitan Crawford | ||
| RCB | Max Melton | Denzel Burke | Ekow Boye-Doe | ||
| P | Blake Gillikin | ||||
| H | Blake Gillikin | ||||
| PR | Greg Dortch | Xavier Weaver | |||
| KR | Greg Dortch | Andre Baccellia | |||
| LS | Aaron Brewer | ||||
| NB | Garrett Williams | Kei'Trel Clark | Darren Hall | ||
| RWR | Michael Wilson | Xavier Weaver | |||
| ROLB | Josh Sweat | BJ Ojulari | Xavier Thomas | ||
| K | Chad Ryland | ||||
| LWR | Marvin Harrison | Simi Fehoko | Tejhaun Palmer | ||
| LOLB | Baron Browning | Zaven Collins | Jordan Burch | ||
| NT | Dalvin Tomlinson | Dante Stills | PJ Mustipher | Kyon Barrs |
Team Stats
Seahawks vs. Cardinals Odds Comparison
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Seahawks at Cardinals Team Totals
MatchupOverUnder | ||
|---|---|---|
Seahawks 2-1 | N/A | N/A |
Cardinals 2-1 | N/A | N/A |