Bills vs. Texans Odds & Betting Predictions - September 13, 2026

Bills at Texans

5:00 pm • CBS
0 - 0

Bills at Texans Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Bills
0-0
-1.5
-1.5-105
o44.5-110
-117
Texans
0-0
u44.5
+1.5-115
u44.5-110
-102
location pinSunday 5:00 p.m.
September 13, 2026
Reliant StadiumHouston
Bills vs. Texans Expert Picks
Sean Zerillo
Sean Zerillo
Last 30d: 53-82-3 (-6.3u)
Under 44.5-105
0.26u
Mjaybrod
Mjaybrod
Last 30d: 27-19-1 (+7.5u)
Over 44.5+100
1u
Prop Bomb 🏝
Prop Bomb 🏝
Last 30d: 8-8-0 (+1.0u)
HOU -102
1.02u
From The Lunch Break! Every Fridays 1PM EST Buffalo opened -1.5 and I have this closer to a true pick. Houston's front with Will Anderson Jr. and Derek Stingley Jr. has been Josh Allen's problem since before DeMeco Ryans got there, and Buffalo is the team in transition with Sean McDermott out, Joe Brady in, and Matt Milano and Taron Johnson gone off a defense that graded 20th in EPA. Jayden Higgins tore his ACL and is done for the year, which is a real hole behind Nico Collins, but Stroud has his healthy receivers this week and David Montgomery to take carries off him. I posted this at +106 and it's near even money now, so play it to -110 and pass below that.
Jeremiah Rose
Jeremiah Rose
Last 30d: 18-20-0 (-0.7u)
Under 44.5-110
1u
Vegas Refund
Vegas Refund
Last 30d: 8-6-0 (+1.3u)
HOU +1.5-110
1.1u
The Degenerates
The Degenerates
Last 30d: 48-44-1 (+0.6u)
Under 45-110
1.1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 19-24-0 (+7.9u)
HOU u22.5-108
1.08u
K.Coleman Anytime TD Scorer Yes+700
0.25u
Brandon Kravitz
Brandon Kravitz
Last 30d: 22-20-1 (+4.1u)
HOU +1.5-102
1.02u
Adding to position. Favorite bet on the board among the lines that haven’t moved on gameday. Happy betting!
Allan Lem
Allan Lem
Last 30d: 28-18-1 (+4.2u)
X.Hutchinson u2.5 Recs-170
0.43u
PredictionPro
PredictionPro
Last 30d: 11-13-0 (-2.5u)
BUF -112
1u
Doug Ziefel
Doug Ziefel
Last 30d: 229-238-11 (+7.6u)
X.Hutchinson u18.5 Rec Yds-115
0.57u
Stuck 🚨
Stuck 🚨
Last 30d: 29-28-2 (-1.2u)
HOU +1.5-112
0.1u
Flipped some from 1H to FG
BUF -112 (1H)
0.1u
Flipped some Texans from 1H to FG. Can still push this too
Kyle Murray
Kyle Murray
Last 30d: 57-65-3 (-6.1u)
BUF -112
1.12u
Collin Whitchurch
Collin Whitchurch
Last 30d: 42-31-1 (+8.5u)
X.Hutchinson u19.5 Rec Yds-113
0.28u
Sean Koerner🔮
Sean Koerner🔮
Last 30d: 9-7-0 (+0.7u)
X.Hutchinson u19.5 Rec Yds-113
0.56u
My goal this week is to have a Prop of the Game for every matchup, and this gets me through the entire early slate. Week 1 is obviously a little different because the edge is naturally lower with so much uncertainty. A lot of people would rather just sit it out and wait for a full week of data, which is completely reasonable. Thats why Week 2 is always one of my favorite weeks. My edge this week is trying to use the last couple months of obsessively tracking camp, preseason, personnel moves, injuries and role changes to get ahead of a few things before we have that clean data. This is one of those spots. When Jayden Higgins went down, Hutchinson looked like the obvious next man up as his direct backup. Then Houston traded for Kayshon Boutte, which made his role a lot murkier. I also think the Texans could lean into more 2TE looks after adding Foster Moreau and drafting Marlin Klein in the second round, while trying to fix a run game that was a disaster last year with David Montgomery now in the mix. The first thing I’ll be watching is who lines up across from Nico Collins on Houston’s first 2TE snap. If it’s Hutchinson, this under could be in trouble. If it’s Boutte, that would suggest the staff is already comfortable with him as the No. 2 WR, which is where I’m leaning. That could leave Hutchinson splitting 3WR snaps with Jaylin Noel, who I think is a better fit as the No. 3 alongside Nico/Boutte. I could easily see Hutchinson finishing 1/10/0 or 3/30/0, which is why I’d rather play Under 19.5 yards than pay -180 on Under 2.5 receptions. I have him closer to 17 yards with around a 58% chance to stay under. Wider range of outcomes than usual, but that’s kind of the entire Week 1 exercise.
Frank Ammirante
Frank Ammirante
Last 30d: 243-294-6 (-40.1u)
K.Boutte u27.5 Rec Yds-114
1.14u
Matt DiLeo
Matt DiLeo
Last 30d: 50-30-1 (+8.8u)
D.Montgomery o7.5 Rec Yds-114
0.5u
D.Montgomery o1.5 Recs+100
0.5u
Brandon Anderson
Brandon Anderson
Last 30d: 2-0-0 (+1.2u)
Under 44.5+100
1u
It shouldn't come as a surprise that I love this under, seeing as I ranked the Bills 18th in my preseason power rankings and bet them to miss the playoffs. I have huge doubts about everything in Buffalo outside of Josh Allen. DC Jim Leonhard's defense just isn't very talented, and I do not believe in their coaching or special teams. One man alone does not make a team. Houston's run defense is elite and will not let Joe Brady's power run game dictate the pace. While Allen is typically excellent against top defenses, he struggles mightily against Houston's man coverage. In 37 games over the last two years, Allen's games against the Texans rank 35th and 36th in dropback success rate. He even lost to Davis Mills last year! This game just screams under. It's easy to imagine a cagey, playoff-like atmosphere. Week 1 unders from 41 to 45.5 are 94-56-1 (64%). Allen road unders are 36-24-2 (60%), and C.J. Stroud home unders are an incredible 17-6 (74%). This is simply what both teams do in this spot. I also think the wrong team is favored—I actually make this line Texans -4. Historically, close lines don't necessarily mean close games. Since 2015, home 'dogs of less than 3 points have won outright 138 times — but in 84 of those wins (60%) were by a comfortable seven or more points. Eight of Houston's 13 wins last season came by 7+ points. I'm skipping the +1.5; if we are going to be right, let's really be right.
HOU -6.5+255
0.5u
It shouldn't come as a surprise that I love this under, seeing as I ranked the Bills 18th in my preseason power rankings and bet them to miss the playoffs. I have huge doubts about everything in Buffalo outside of Josh Allen. DC Jim Leonhard's defense just isn't very talented, and I do not believe in their coaching or special teams. One man alone does not make a team. Houston's run defense is elite and will not let Joe Brady's power run game dictate the pace. While Allen is typically excellent against top defenses, he struggles mightily against Houston's man coverage. In 37 games over the last two years, Allen's games against the Texans rank 35th and 36th in dropback success rate. He even lost to Davis Mills last year! This game just screams under. It's easy to imagine a cagey, playoff-like atmosphere. Week 1 unders from 41 to 45.5 are 94-56-1 (64%). Allen road unders are 36-24-2 (60%), and C.J. Stroud home unders are an incredible 17-6 (74%). This is simply what both teams do in this spot. I also think the wrong team is favored—I actually make this line Texans -4. Historically, close lines don't necessarily mean close games. Since 2015, home 'dogs of less than 3 points have won outright 138 times — but in 84 of those wins (60%) were by a comfortable seven or more points. Eight of Houston's 13 wins last season came by 7+ points. I'm skipping the +1.5; if we are going to be right, let's really be right.
Grant Neiffer
Grant Neiffer
Last 30d: 30-105-2 (+14.2u)
D.Moore Anytime TD Scorer Yes+270
0.25u
Doug Ziefel
Doug Ziefel
Last 30d: 229-238-11 (+7.6u)
J.Cook u2.5 Recs+115
0.43u
K.Boutte o2.5 Recs+180
0.28u
Derek Carty
Derek Carty
Last 30d: 16-24-1 (+2.2u)
J.Cook u2.5 Recs+122
1u
There may be some value on the receptions prop for James Cook III. THE BLITZ is projecting him to record 2.31 receptions, and the oddsmakers are implying 3.28. The model believes there is a 62% chance he records fewer than 2.5 receptions. If you can get the under at +122 or better, there is some great value here. This play is good down to at least -116. Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
The Favorites Podcast
The Favorites Podcast
Last 30d: 2-2-0 (+0.4u)
HOU +1.5-115
1u
Babs .
Babs .
Last 30d: 25-27-0 (-7.4u)
J.Allen o0.5 Int+115
1u
Stuck 🚨
Stuck 🚨
Last 30d: 29-28-2 (-1.2u)
HOU +0.5 (1H)-120
0.55u
RoyalsProps
RoyalsProps
Last 30d: 8-11-0 (-4.3u)
D.Montgomery o7.5 Rec Yds-114
1.14u
OldSchool0909
Last 30d: 88-103-1 (-9.2u)
HOU +1.5-120
1u
Brandon Kravitz
Brandon Kravitz
Last 30d: 22-20-1 (+4.1u)
HOU +1.5+110
1u
Adam Kaufman
Adam Kaufman
Last 30d: 95-105-0 (-26.1u)
BUF -110
1.1u

Bills vs. Texans Previews & Analysis

  • Bills vs. Texans: 2 Ways to Bet Houston in Week 1 article feature image

    Bills vs. Texans: 2 Ways to Bet Houston in Week 1

    Stuckey
    Sep 13, 2026 UTC
  • NFL Betting Primer: Trends, Stats, Systems for Every Game article feature image

    NFL Betting Primer: Trends, Stats, Systems for Every Game

    Evan Abrams
    Sep 13, 2026 UTC
  • Anderson's Week 1 Mega-Preview: Props, Parlays, More! article feature image

    Anderson's Week 1 Mega-Preview: Props, Parlays, More!

    Brandon Anderson
    Sep 13, 2026 UTC
  • Koerner's Week 1 Pick'em & Confidence Rankings article feature image

    Koerner's Week 1 Pick'em & Confidence Rankings

    Sean Koerner
    Sep 13, 2026 UTC
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Bills vs. Texans Props

Prop Projections

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Bills vs. Texans Public Betting Percentages

Away Logo

Bills

Public

55%

Bets%

45%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Texans
N/AN/AN/AN/AN/A
Bills
N/AN/AN/AN/AN/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Texans
N/AN/AN/AN/AN/A
Bills
N/AN/AN/AN/AN/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Texans
N/AN/AN/AN/AN/A
Bills
N/AN/AN/AN/AN/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 28th@CARL 13-16-1.5 LU 37CAR -118
Aug 21stLVL 20-22-1 LO 39.5LV +112
Aug 14thLACL 7-27-1.5 LU 38.5LAC -115
Jan 18th@NEL 16-28+3.5 LO 41NE +150
Jan 13th@PITW 30-6-3 WU 38.5HOU -155

Bills vs. Texans Injury Updates

Bills Injuries

  • Ty Johnson
    RB

    Johnson is questionable with hamstring

    Questionable

Texans Injuries

    Team Stats
    30
    Total Yards
    0
    5
    Total Plays
    0
    3
    YDS
    0
    1/1
    Comps/Atts
    0/0
    3
    YPA
    0
    0/0
    TDs/INTs
    0/0
    0/0
    Sacks/Yards
    0/0
    27
    Rush Yards
    0
    4
    Attempts
    0
    6.75
    YPC
    0
    0
    TDs
    0

    Turnovers

    0
    Fumbles Lost
    0
    0
    Interceptions
    0

    Efficiency

    0/0 0%
    Redzone
    0/0 0%
    0/0 0%
    3rd Down
    0/0 0%
    0/0 0%
    4th Down
    0/0 0%

    First Downs

    2
    Total
    0
    1
    Pass
    0
    1
    Rush
    0
    0
    Penalty
    0
    0/0
    Penalties/Yards
    0/0
    2:28
    Possession
    00:00

    Bills vs. Texans Odds Comparison

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    Bills at Texans Team Totals

    MatchupOverUnder
    Bills
    0-0
    N/A
    N/A
    Texans
    0-0
    N/A
    N/A