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Titans vs. Cardinals Odds & Betting Predictions - October 5, 2025

Titans at Cardinals

8:05 pm • CBS
Stream Live on SiriusXM - Free 3 Month Offer

Tennessee Titans

3-14
@

Arizona Cardinals

8-9

Titans at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Titans
3-14
N/A
N/A
N/A
Cardinals
8-9
N/A
N/A
N/A
location pinSunday 8:05 p.m.
October 05, 2025
State Farm StadiumGlendale

Titans vs. Cardinals Props

Prop Projections

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Titans vs. Cardinals Public Betting Percentages

Away Logo

Titans

Public

Home Logo

Cardinals

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Cardinals are 4-1 in their last 5 games.
  • Cardinals are 5-0 in their last 5 games against the spread
  • Cardinals are 5-3 in their road games against the spread
  • The totals have gone OVER in 1 of Cardinals' last 5 games
  • The totals have gone OVER in 5 of Cardinals' 9 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals		11-66-35-33-47-2
Titans		2-150-82-70-62-9

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals		8-8-15-43-4-15-22-6-1
Titans		10-6-13-4-17-22-48-2-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals		8-9N/AN/A3-44-5
Titans		3-14N/AN/A1-52-9

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jan 5thSFW 47-24-5.5 WO 43.5ARI -240
Dec 29th@LAL 9-13+6.5 WU 48LA +245
Dec 22nd@CARL 30-36-5.5 LO 47CAR -245
Dec 15thNEW 30-17-6 WO 46.5ARI -264
Dec 8thSEAL 18-30-3 LO 45.5SEA -177

Titans vs. Cardinals Injury Updates

Titans Injuries

  • Kevin Zeitler
    G

    Zeitler is out with hamstring

    Out

  • Arden Key
    OLB

    Key is out with hand

    Out

  • Amani Oruwariye
    CB

    Oruwariye is out with foot

    Out

  • Amani Hooker
    S

    Hooker is out with shoulder

    Out

  • L'Jarius Sneed
    CB

    Sneed is out with quad

    Out

  • Treylon Burks
    WR

    Burks is out with knee

    Out

  • Andrew Rupcich
    OL

    Rupcich is out with triceps

    Out

  • Tyjae Spears
    RB

    Spears is out with concussion

    Out

  • Colton Dowell
    WR

    Dowell is out with knee

    Out

  • Jaelyn Duncan
    T

    Duncan is out with shoulder

    Out

  • Titus Leo
    OLB

    Leo is questionable with ankle

    Questionable

  • Otis Reese
    LB

    Reese is out with ankle

    Out

  • Cedric Gray
    LB

    Gray is out with shoulder

    Out

  • Jarvis Brownlee
    DB

    Brownlee is questionable with hip

    Questionable

  • James Williams
    S

    Williams is questionable with knee

    Questionable

Cardinals Injuries

  • Calais Campbell
    DE

    Campbell is questionable with rest

    Questionable

  • Dalvin Tomlinson
    DT

    Tomlinson is questionable with knee

    Questionable

  • James Conner
    RB

    Conner is out with knee

    Out

  • Evan Brown
    OL

    Brown is questionable with neck

    Questionable

  • Sean Murphy-Bunting
    CB

    Murphy-Bunting is questionable with hand

    Questionable

  • Jalen Thompson
    S

    Thompson is questionable with ankle

    Questionable

  • Jonah Williams
    OL

    Williams is questionable with illness

    Questionable

  • Mack Wilson
    LB

    Wilson is questionable with ankle

    Questionable

  • Mykal Walker
    OLB

    Walker is questionable with illness

    Questionable

  • Blake Gillikin
    P

    Gillikin is out with foot

    Out

  • Baron Browning
    OLB

    Browning is questionable with neck

    Questionable

  • Simi Fehoko
    WR

    Fehoko is questionable with elbow

    Questionable

  • Joey Blount
    S

    Blount is out with ribs

    Out

  • Paris Johnson
    OL

    Johnson is out with knee

    Out

  • Michael Wilson
    WR

    Wilson is questionable with hamstring

    Questionable

  • Jammie Robinson
    S

    Robinson is doubtful with knee

    Doubtful

  • Dante Stills
    DE

    Stills is questionable with back

    Questionable

  • Emari Demercado
    RB

    Demercado is out with back

    Out

  • Trey Benson
    RB

    Benson is out with ankle

    Out

  • Elijah Jones
    DB

    Jones is out with ankle

    Out

  • Xavier Thomas
    DE

    Thomas is questionable with back

    Questionable

See more NFL Injuries Right Arrow
Depth Charts
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Starter2ND3RD4TH
QBKyler MurrayClayton Tune
RBJames ConnerTrey BensonEmari DemercadoDeeJay Dallas
WRGreg DortchZay JonesAndre Baccellia
TETrey McBrideElijah HigginsTip ReimanTravis Vokolek
LTParis JohnsonKelvin BeachumChristian Jones
LGEvan BrownIsaiah Adams
CHjalte FroholdtTrystan Colon
RGWill HernandezJon Gaines
RTJonah WilliamsJackson Barton
LDEBilal NicholsDarius RobinsonBen Stille
RDEJustin JonesL.J. CollierDante Stills
WLBKyzir WhiteKrys Barnes
MLBMack WilsonOwen Pappoe
LCBSean Murphy-BuntingElijah Jones
SSBudda BakerDadrion Taylor-DemersonAndre ChachereDarren Hall
FSJalen ThompsonJoey Blount
RCBMax MeltonStarling Thomas
PBlake Gillikin
HBlake Gillikin
PRGreg DortchDeeJay DallasXavier WeaverEmari Demercado
KRGreg DortchDeeJay DallasXavier WeaverEmari Demercado
LSAaron Brewer
NBGarrett WilliamsKei'Trel ClarkJaden Davis
LWRMarvin HarrisonXavier Weaver
RWRMichael WilsonZach PascalTejhaun Palmer
NTRoy LopezKhyiris TongaNaquan Jones
KMatt Prater
ROLBZaven CollinsJesse Luketa
LOLBDennis GardeckVictor DimukejeXavier Thomas

Titans vs. Cardinals Odds Comparison

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Titans at Cardinals Team Totals

MatchupOverUnder
Titans
3-14
N/A
N/A
Cardinals
8-9
N/A
N/A