NFL Odds, Picks, Predictions: Your Guide To Betting Cardinals-Browns, Cowboys-Patriots & Raiders-Broncos

NFL Odds, Picks, Predictions: Your Guide To Betting Cardinals-Browns, Cowboys-Patriots & Raiders-Broncos article feature image

Getty Images. Pictured: Rams QB Jared Goff, Cowboys QB Dak Prescott

  • With the early afternoon games already underway, there are still three more late afternoon games to bet on.
  • Find Week 6 NFL odds and picks for Cardinals-Browns, Cowboys-Patriots and Raiders-Broncos below.

NFL Odds, Picks, Predictions

Click on a matchup to skip to that matchup preview and pick.
4:05 p.m. ET
4:25 p.m. ET
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Cardinals at Browns Odds

Cardinals Odds+3.5
Browns Odds-3.5
Time4:05 p.m. ET
Odds via DraftKings. Get up-to-the-minute NFL odds here.

Michael Arinze: There's been plenty of action on this game, and as I write this, the Browns have been bet up to 3.5 (check real-time NFL odds here).

I agree with the move — my assessment centers on the windy conditions that could plague a warm-weather team like the Cardinals. And it wouldn't surprise me if there's more to Murray's shoulder injury. These issues, combined with losing their primary play-caller, seem like a lot to overcome for the Cardinals on the road. However, the Browns were available at -2.5 earlier in the week, so the value is completely gone at the current number.

If you're looking to get involved in this game, you might want to consider playing the total. While our analysis leans to the Browns, it correlates nicely with the under, given the windy forecast and the injury report.

Our Action Labs database shows that the total is 6-1 to the under when the Browns are at home with an opening total of at least 50 points. But, like the point spread, the total has also moved as it was as high as 54 earlier in the week, but we can look to gain some of that back by playing the under as part of a six-point, two-team teaser.

BetMGM is still offering a total of 49 as of writing, so we can bring that number up to 55 and pair that with another leg of your liking. As for me, I prefer to go with the Packers against the Bears. Green Bay's covered the spread in each of its last four games, and it's also covered the spread in the previous four meetings against Chicago. Moreover, it's 17-5 ATS on the road in Chicago.

I love the idea of bringing the Packers' six-point spread down to a pick'em and pairing it with the under in the Browns game.

Pick: Tease Cardinals-Browns under from 49 to 55; pair with Packers from -6 to pick'em

Read the full Cardinals vs. Browns preview or return to the table of contents

Raiders at Broncos Odds

Raiders Odds+4
Broncos Odds-4
Time4:25 p.m. ET
Odds via BetRivers. Get up-to-the-minute NFL odds here.

Raheem Palmer: The Raiders are in a bad spot, but even more jarring is that they have lost every single first half this season, and now they’ll be taking on a divisional opponent desperate for a win in the Broncos.

I’ll back Denver in this spot to get out to a fast start against a Vegas team that has started slowly all season.

Pick: Broncos 1H -2.5 (-110)

Read the full Raiders vs. Broncos preview or return to the table of contents

Editor's note: The following previews were for games that kicked off at 1 p.m. ET.

NFL Odds, Picks, Predictions

Click on a matchup to skip to that matchup preview and pick.
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Chiefs at Washington Odds

Chiefs Odds-6.5
Washington Odds+5.6
Time1 p.m. ET
Odds via BetRivers. Get up-to-the-minute NFL odds here.

Michael Arinze: The profile of this game suggests we could see plenty of points. Thus, it makes sense to look for derivatives that correlate with the over in mind. As a result, the first thing I'd look to do is get involved with the total.

We highlighted the defensive issues of both teams in our full preview, so neither offense should have any problems moving the ball. In Kansas City's last five games, the total is 4-1 to the over and 4-0 in Washington's previous four games. Some sportsbooks are offering this total at 54 as of writing, but that number seems short to me, so I'd look to play this over at 54.5 or better.

Second, I like Patrick Mahomes to go over his passing touchdown prop, which BetMGM lists at 2.5 (-135). The Chiefs quarterback threw for two touchdowns against the Bills — he was critical of his play in that game, and it was the first time all season he didn't throw for at least three touchdowns, which makes this an excellent spot for him to bounce back.

Kansas City should also be less inclined to run the ball, even in goal-line situations, with Clyde Edwards-Helaire sidelined. Thus, there's a more significant potential the Chiefs will keep the ball in Mahomes' hands.

Lastly, l like BetMGM's first half prop of both teams to score at least 10 points (+100) in the first half. Both teams have combined to reach this mark in eight of their 10 games this season.

3 Picks: Over 54 | Mahomes Over 2.5 Pass TDs | Both teams to score at least 10 1H points (0.5 units for each)

Read the full Chiefs vs. Washington preview or return to the table of contents

Rams at Giants Odds

Rams Odds-9
Giants Odds+9
Time1 p.m. ET
Odds via DraftKings. Get up-to-the-minute NFL odds here.

Joe Klein: Were we to have a healthy Daniel Jones in this game, I would price it at LA -7, which would have been in line with the lookahead. He seems to be trending in as of writing, which on the surface is a boost for the Giants. But if he does go, they would likely be conservative and limit his running, which hurts their overall offensive profile.

If Jones is confirmed in, this market will move towards New York, and we're already seeing that with FanDuel down to Rams -8.

However, I don't think we can expect an average performance out of a banged-up Jones. This Rams defense should be able to get right, and the Giants will struggle to keep up with this offense.

The Rams should be able to name their score in this game. Their offensive line has a major mismatch against a Giants defensive line that has struggled to pressure anyone. Furthermore, Los Angles is coming off some extra rest, having played on Thursday night back in Week 5, which should give Sean McVay a bit of extra time to scheme against a porous secondary.

I like the Rams at the price of -8, but we may get better. Keep an eye for market move and pounce if this continues to trickle down.

Pick: Rams -8

Read the full Rams vs. Giants preview or return to the table of contents

Packers at Bears Odds

Packers Odds-5.5
Bears Odds+5.5
Time1 p.m. ET
Odds via DraftKings. Get up-to-the-minute NFL odds here.

Brandon Anderson: Early in the week, I loved the Packers. They were my lookahead pick on the podcast a week ago as I expected a big win in Week 5 and the Bears to lose ugly in Las Vegas. Well, that didn't happen. The Packers were lucky to escape with a win over the Bengals after missing three game-winning kicks late, and the Bears dominated the 3-1 Raiders on the road.

I'm starting to wonder if we're just blindly trusting the green and gold jerseys a little too much.

Green Bay has not been as dominant as the 4-1 record looks, and Chicago has the exact sort of formula you'd want from an underdog against this team. The Bears have been running the ball really well and should attack this struggling Packers front seven while the defense will give Aaron Rodgers all he can handle.

The Packers are 4-1 ATS, too, and that's pretty surprising for a team with a negative point differential. Historically, it has been very profitable to fade great ATS teams in Weeks 6 and 7, right about that mark of the season when the public gets a little overconfident in what they've seen. Per our data at Action Labs, teams facing opponents with 80-99% ATS records in their sixth or seventh game are an impressive 63-34-3 ATS (64.9%), covering by 3.3 points.

Now that this line is nearly a touchdown — with the Packers looking a bit overvalued and the Bears defense playing so well and at home in a division rivalry — this just feels like too many points. I'm still confident the Packers are the better team, but I have to play the number and take the Bears here.

You could also play the Packers to win by six or fewer points at +310 at BetMGM. That's what I played, as I can get a Bears cover but also a Packers win, and it's a great middle opportunity if you want to risk playing both sides.

Picks: Bears +6 & Packers to win by 1-6 (+310)

Read the full Packers vs. Bears preview or return to the table of contents

Bengals at Lions Odds

Bengals Odds-3.5
Lions Odds+3.5
Time1 p.m. ET
Odds via DraftKings. Get up-to-the-minute NFL odds here.

Mike Vitanza: Through five games, Ja'Marr Chase has established himself as the top passing option for Joe Burrow and this Bengals offense. Part of that can be attributed to the chemistry the duo developed while at LSU, but the majority is due to the elite skill and speed combination that Chase provides.

Still relatively early in his rookie season, Chase has compiled an impressive 456 receiving yards and five touchdowns. In fact, he’s averaging 91 receiving yards per game and has eclipsed 77 yards in three of five games. Those are elite numbers for any player, never mind a rookie with just five starts under his belt.

This week the matchup could not be any better. Not only does he have one of the best individual matchups of any player this week, but he’ll also have it against one of the worst secondaries in all of football.

The Lions have shown a penchant for keeping games close this season, so negative game script should not affect the passing volume for the Bengals here. As such, I expect their passing attack to be firing away late into the fourth quarter.

I’m taking Chase to surpass 73.5 receiving yards and would be comfortable playing it all the way up to that 77-yard mark.

Pick: Ja’Marr Chase Over 73.5 Receiving Yards at PointsBet

Read the full Bengals vs. Lions preview or return to the table of contents

Texans at Colts Odds

Texans Odds+10
Colts Odds-10
Time1 p.m. ET
Odds via BetRivers. Get up-to-the-minute NFL odds here.

Phillip Kall: The Colts have too good of a team to not control this game. They may have four losses but those came against the Seahawks, Titans, Rams and Ravens — all teams we expected to be in the playoff hunt. And it should be noted that the Colts had leads against three of them.

The main issue for Indianapolis is its offensive production has not led to scoring the way it should. The Colts rank fourth plays per drive and ninth in yards per drive, but just 16th in points per drive. Per Flurry Sports, Indianapolis ranks last in red-zone touchdown percentage at 36.8%. The Colts' inability to finish drives too often leaves the door open for opponents to strike back. Monday night is the perfect example.

Indy’s inability to light up the scoreboard, paired with PFF's second-worst coverage unit, is not a recipe to cover. Davis Mills looked much better against New England and now gets a pretty good matchup on the road.

The Texans offense still might be pushing average at best, but that should be enough to overcome the Colts' lack of defense.

This spread is simply too much for a team that struggles to score and is weak on the backend. Houston might lose, but it should keep it close enough to cover.

Pick: Texans +10 (no further)

Read the full Texans vs. Colts preview or return to the table of contents

Chargers at Ravens Odds

Chargers Odds+2.5
Ravens Odds-2.5
Time1 p.m. ET
Odds via DraftKings. Get up-to-the-minute NFL odds here.

Raheem Palmer: I faded the Chargers last week because I thought the Browns had major advantages with their ability to run the ball. While it didn't work out for us, Cleveland held a 14-point second-half lead before Justin Herbert and LA mounted a comeback.

Los Angeles faces a fourth straight strong opponent, and for this one it has to fly east and deal with a quarterback like Lamar Jackson. I have trouble believing this struggling Chargers defense has any chance of slowing him down.

At some point, regression has to kick in for Los Angeles' offense, too.

I'm betting it starts here.

Pick: Ravens -2.5

Read the full Chargers vs. Ravens preview or return to the table of contents

Vikings at Panthers Odds

Vikings Odds-2.5
Panthers Odds+2.5
Time1 p.m. ET
Odds via DraftKings. Get up-to-the-minute NFL odds here.

Billy Ward: Normally, a 3-2 home team would be expected to be favored against a 2-3 opponent. Of course, the injury situation is baked in.

Most books had the Vikings listed as -2.5 favorites late in the week, but BetMGM was offering them at -1.5 (-105) as late as Friday. I don't love the bet — the Vikings could very well struggle to move the ball throughout this game. However, when we're getting a strong signal from the market as a whole, it's generally worth picking on the outlier.

If you have access to the number still, I would bet the Vikings spread down to -1.5 (-110). Any further than that, though, and I don't see any value left.

Pick: Vikings to -1.5 (-110) if available

Read the full Vikings vs. Panthers preview or return to the table of contents

Cowboys at Patriots Odds

Cowboys Odds-3.5
Patriots Odds+3.5
Time4:25 p.m. ET
Odds via DraftKings. Get up-to-the-minute NFL odds here.

Brandon Anderson: On our podcast last week, Raheem Palmer and I loved the Cowboys as a lookahead play. Dallas was just a one-point favorite, basically a moneyline pick. But after another comfortable Cowboys win and an ugly Patriots game against the Texans, this line jumped above a field goal and that shifted the balance.

I have this line at Dallas -3.5, right where it's settled, so that doesn't leave a ton of value on either side. The Cowboys are clearly the better team right now and I'd feel pretty good backing them under a field goal, but at 3.5, that hook is just enough to give me pause.

How many times have we seen an underdog Bill Belichick team against a great offense? You know he'll have a scheme ready to go to keep his team in the game, and you know the offense will keep the clock moving — probably with short Mac Jones passes, in this case — limit possessions, and put the pressure on the favorite as the game stays close. That's exactly what we saw against the Bucs just two weeks ago.

This spread feels just right.  If the line drops to a field goal, I might be willing to give Dallas a shot, but I'm not sure there's a ton of value on the spread.

Instead, I'll take the first-half under 24. New England games are averaging only 18.8 points per half, and Pats first halves have seen 24 or fewer points in all five games this season.

If the Cowboys run game does take over eventually, it may be in the second half once the Patriots defense wears down. I trust Belichick and the Patriots defense to limit things early on, but the Cowboys talent could win out through four quarters.

Pick: 1H Under 24 (+100)

Read the full Cowboys vs. Patriots preview or return to the table of contents

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