NFL Odds, Picks & Predictions: Your NFL Week 5 Betting Cheat Sheet (Sunday, Oct. 11)

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  • Want to get in on the betting action for the Sunday NFL games? We have you covered.
  • We have everything you could need for Week 5, including picks for each game, expert bets, sharp plays, prop bets, fantasy football advice, survivor pool recommendations, and pick'em confidence ratings.
  • Check out all of our breakdowns below.

Not sure where to start with all the betting advice for Week 5?

We’ve compiled all of our best content into a simple cheat sheet so you can find exactly what you’re looking for, from odds and picks to previews and power ratings to survivor pool plays and more.

Find everything you need to bet Sunday’s 10-game main slate below, including information on how and where to bet legally in your state.

Week 5 NFL Odds

Odds below as of early Sunday and via DraftKings, where you can get up to a $1,000 sign-up bonus. Compare real-time lines from various sportsbooks using our NFL Odds page.

Spread
Total
Kickoff
Preview
Raiders at Chiefs (-11.5) [Bet Now]
55 [Bet Now]
1 p.m. ET
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Eagles at Steelers (-7) [Bet Now]
44 [Bet Now]
1 p.m. ET
Read More
Panthers at Falcons (-2.5) [Bet Now]
53.5 [Bet Now]
1 p.m. ET
Read More
Cardinals (-7) at Jets [Bet Now]
47.5 [Bet Now]
1 p.m. ET
Read More
Rams (-7.5) at Washington [Bet Now]
46.5 [Bet Now]
1 p.m. ET
Read More
Bengals at Ravens (-11.5) [Bet Now]
50.5 [Bet Now]
1 p.m. ET
Read More
Jaguars at Texans (-5.5) [Bet Now]
54.5 [Bet Now]
1 p.m. ET
Read More
Dolphins at 49ers (-8.5) [Bet Now]
51 [Bet Now]
4:05 p.m. ET
Read More
Giants at Cowboys (-8.5) [Bet Now]
53.5 [Bet Now]
4:25 p.m. ET
Read More
Colts (-1) at Browns [Bet Now]
48 [Bet Now]
4:25 p.m. ET
Read More

Week 5 NFL Picks

Below are our staff’s favorite bets for Sunday. Click on a pick to read more.

PICK
PICK
BET NOW
Panthers-Falcons Over 53.5
1 p.m. ET
BetMGM
Panthers +2 at Falcons
1 p.m. ET
BetMGM
Steelers -7 vs. Eagles
1 p.m. ET
BetMGM
Eagles-Steelers 1H Under 22.5
1 p.m. ET
WilliamHill
Browns ML -110 vs. Colts
4:25 p.m. ET
BetMGM
Vikings +7 at Seahawks
8:20 p.m. ET
PointsBet

More Expert NFL Picks

Three of the four analysts behind our NFL Power Ratings are break down their Week 5 picks. Here are their records on NFL bets tracked in the Action app as well as links to their full cards:

NFL Sharp Picks

Raiders-Chiefs. Colts-Browns. PJ Walsh uses our NFL PRO Report to detail how pros are betting these Week 5 games.

NFL Prop Bets & Picks

Some of the most valuable bets this season have been on rookie wide receivers before they break out. Sean Koerner highlights two more opportunities to buy low on Year 1 wideouts and all 10 (!) of his favorite NFL prop bets for Sunday.

Five more props are showing value according to our FantasyLabs NFL Player Prop Tool, which is powered by Koerner’s projections. Matt LaMarca outlines which.

NFL Pick ‘Em Rankings

Straight up. Against the spread. Whether you’re playing in your office’s (virtual) pool or in a higher-stakes contest, Sean Koerner has you covered with his Week 5 Pick ‘Em Confidence Ratings.

NFL Survivor Pool Recommendation

What do the numbers suggest is the top survivor pool play for Week 5? Travis Reed shares his recommendation.

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NFL Injury Report

We’re tracking all the key injuries with real-time updates throughout Sunday as final actives/inactives are announced. Find the latest news.

How & Where To Bet On the NFL

You can find reviews of the best online sportsbooks in your states, their latest promos and more in this hub.

Legal online sports betting is currently available in the following states:

And here are some of the top online sportsbooks:

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